Indomethacin is the only medicine that works for an acute gout flare up. Motrin and Naprosyn have never worked for me (since it first came out, docs are always trying to foist Naprosyn off on me. All it does is make me very irritated. either a side effect or the effect of no relief). I've also tried other NSAIDs with no relief. I'm prescribed 75mg three times a day for the first two days and then twice a day for two to three more and finally down to once a day for the remainder of the week to 10 days it takes to tame down the flare up.
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